Oxidative rearrangement of cyclobutanone derived N,O-ketals leading to pyrrolidone derivatives.
نویسندگان
چکیده
A halogen-induced oxidative rearrangement of N,O-ketals prepared from cyclobutanones, leading to pyrrolidone derivatives, is developed. The reaction proceeds via an iminium ether intermediate and, depending on the reaction medium, two types of pyrrolidone derivative, containing a halogen atom or hydroxyl group, can be obtained.
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عنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 63 4 شماره
صفحات -
تاریخ انتشار 2015